HEPATITIS B Management
information taken from https://www.bashhguidelines.org/current-guidelines/viral-hepatitis/download-the-full-guideline/?show=1297 . Hepatitis B virus infection 3.1 Aetiology Hepatitis B is an hepadna (DNA) virus. It is endemic worldwide, apart from isolated communities, with very high carriage rates (up to 20%) particularly in South and East Asia, but also in Southern Europe, Central and South America, Africa and Eastern Europe. In the UK, HBV sero-prevalence varies from 0.010.04% in blood donors and to >1% in PWID and MSM. In 2015 5090 HBV cases were notified in England and Wales of which 457 were acute infections[52a]. There are 8 distinct genotypes (A-H) which vary in geographical distribution, pathogenicity and treatment susceptibility [53]. 3.2 Transmission • Sexual transmission occurs in unvaccinated/non-immune MSM and...